5m9t

X-ray diffraction
2.2Å resolution

Human angiogenin ALS variant H114R

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137273 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Angiogenin Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 14.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03950 (Residues: 25-147; Coverage: 100%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 81.426Å b: 81.426Å c: 85.985Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.186 0.182 0.236
Expression system: Escherichia coli BL21(DE3)