Function and Biology Details
Reaction catalysed:
Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domain:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Uricase (preferred)
PDBe Complex ID:
PDB-CPX-179513 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uricase
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 298 amino acids
Theoretical weight: 34.24 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Uricase
Structure domains: Urate Oxidase;
Length: 298 amino acids
Theoretical weight: 34.24 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q6DG85 (Residues: 1-298; Coverage: 100%)
Sequence domains: Uricase
Structure domains: Urate Oxidase;
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
