› 5l5k

X-ray diffraction
7.5Å resolution

Plexin A4 full extracellular region, domains 1 to 10, data to 7.5 angstrom, spacegroup P4(1)

Released:
DOI: 10.2210/pdb5l5k/pdb
PDB entry 5l5k coloured by chain, front view.
PDB entry 5l5k coloured by chain, side view.
PDB entry 5l5k coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Basis for Plexin Activation and Regulation.
Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY
Neuron 91 548-60 (2016)
PMID: 27397516

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182370 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plexin-A4 Chain: A
Molecule details ›
Chain: A
Length: 1207 amino acids
Theoretical weight: 134.81 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q80UG2 (Residues: 36-1229; Coverage: 64%)
Gene names: Kiaa1550, Plxna4
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P41
Unit cell:
a: 220.593Å b: 220.593Å c: 65.938Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.354 0.353 0.371
Expression system: Homo sapiens

Quick links

Citations

11 review citations

Macrophage Clearance of Apoptotic Cells: A Critical Assessment.
Gordon et al. (2018)
10 more

11 mentions without citation

TREM2-Ligand Interactions in Health and Disease.
Kober et al. (2017)
10 more