5ka5

X-ray diffraction
1.8Å resolution

HIV-1 gp41 variant V549E resistance mutation

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-137976 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.62 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P04578 (Residues: 543-582, 625-661; Coverage: 9%)
Gene name: env
Sequence domains: Retroviral envelope protein
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: R3
Unit cell:
a: 40.716Å b: 40.716Å c: 115.521Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.187 0.222
Expression system: Escherichia coli