Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
HipBA toxin-antitoxin complex and DNA (preferred)
PDBe Complex ID:
PDB-CPX-118901 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (4 distinct):
Serine/threonine-protein kinase toxin HipA
Molecule details ›
Chains: A, D
Length: 448 amino acids
Theoretical weight: 50.42 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 448 amino acids
Theoretical weight: 50.42 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P23874 (Residues: 2-440; Coverage: 100%)
Sequence domains:
Antitoxin HipB
Molecule details ›
Chains: B, P
Length: 91 amino acids
Theoretical weight: 10.34 KDa
Source organism: Escherichia coli MP020980.2
Expression system: Escherichia coli
UniProt:
Sequence domains: Helix-turn-helix
Structure domains: lambda repressor-like DNA-binding domains
Length: 91 amino acids
Theoretical weight: 10.34 KDa
Source organism: Escherichia coli MP020980.2
Expression system: Escherichia coli
UniProt:
- Canonical: P23873 (Residues: 1-88; Coverage: 100%)
Sequence domains: Helix-turn-helix
Structure domains: lambda repressor-like DNA-binding domains
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.3.1
Spacegroup:
P21212
Expression system: Escherichia coli
