› 5jx2

X-ray diffraction
2.05Å resolution

Crystal structure of MglB-2 (Tp0684) from Treponema pallidum

Released:
DOI: 10.2210/pdb5jx2/pdb
PDB entry 5jx2 coloured by chain, front view.
PDB entry 5jx2 coloured by chain, side view.
PDB entry 5jx2 coloured by chain, top view.
Source organism: Treponema pallidum subsp. pallidum str. Nichols
Primary publication:
The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
Brautigam CA, Deka RK, Liu WZ, Norgard MV
PLoS One 11 e0161022 (2016)
PMID: 27536942

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170622 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose/galactose-binding lipoprotein Chain: A
Molecule details ›
Chain: A
Length: 387 amino acids
Theoretical weight: 41.82 KDa
Source organism: Treponema pallidum subsp. pallidum str. Nichols
Expression system: Escherichia coli
UniProt:
  • Canonical: Q08255 (Residues: 36-403; Coverage: 97%)
Gene names: TP_0684, mglB, tpp38
Sequence domains:
Structure domains: Rossmann fold

Ligands and Environments

3 bound ligands:
Ligand CA 1 x CA
Ligand BTB 1 x BTB
Ligand EDO 2 x EDO
1 modified residue:
Ligand ALY 1 x ALY

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 77.556Å b: 130.025Å c: 88.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.186 0.226
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Treponema pallidum Outer Membrane.
Radolf et al. (2018)
1 more

1 mention without citation

The Tp0684 (MglB-2) Lipoprotein of Treponema pallidum: A Glucose-Binding Protein with Divergent Topology.
Brautigam et al. (2016)