5jw3

X-ray diffraction
3.75Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-212371 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (6 distinct):
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 316 amino acids
Theoretical weight: 34.53 KDa
Source organism: Influenza A virus (A/turkey/Italy/214845/2002(H7N3))
UniProt:
  • Canonical: Q6GYW3 (Residues: 19-334; Coverage: 56%)
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chain: B
Molecule details ›
Chain: B
Length: 170 amino acids
Theoretical weight: 19.68 KDa
Source organism: Influenza A virus (A/turkey/Italy/214845/2002(H7N3))
UniProt:
  • Canonical: Q6GYW3 (Residues: 340-509; Coverage: 30%)
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B
MEDI8852 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 228 amino acids
Theoretical weight: 24.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
MEDI8852 light chain Chain: L
Molecule details ›
Chain: L
Length: 206 amino acids
Theoretical weight: 22.45 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P321
Unit cell:
a: 143.99Å b: 143.99Å c: 130.92Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.224 0.263
Expression system: Homo sapiens