› 5i8x

X-ray diffraction
1.89Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165777 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calcium-mediated lectin domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 114 amino acids
Theoretical weight: 11.73 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HYN5 (Residues: 2-115; Coverage: 99%)
Gene names: PA3361, lecB
Sequence domains: Fucose-binding lectin II (PA-IIL)
Structure domains: Calcium-mediated lectin
DLS-LYS-CYS-LYS-LEU-CYS-LYS-LYS-NH2 Chain: E
Molecule details ›
Chain: E
Length: 9 amino acids
Theoretical weight: 1.05 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand ZDC 4 x ZDC
Ligand CA 8 x CA
1 modified residue:
Ligand DLS 1 x DLS

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21
Unit cell:
a: 48.424Å b: 79.202Å c: 52.627Å
α: 90° β: 94.52° γ: 90°
R-values:
R R work R free
0.185 0.183 0.223
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

4 review citations

The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions.
Gan et al. (2021)
3 more