› 5i1r

Hybrid

Quantitative characterization of configurational space sampled by HIV-1 nucleocapsid using solution NMR and X-ray scattering

Released:
DOI: 10.2210/pdb5i1r/pdb
PDB entry 5i1r coloured by chain, ensemble of 21 models, front view.
PDB entry 5i1r coloured by chain, ensemble of 21 models, side view.
PDB entry 5i1r coloured by chain, ensemble of 21 models, top view.
Source organism: HIV-1 M:B_HXB2R
Primary publication:
Quantitative Characterization of Configurational Space Sampled by HIV-1 Nucleocapsid Using Solution NMR, X-ray Scattering and Protein Engineering.
Deshmukh L, Schwieters CD, Grishaev A, Clore GM
Chemphyschem 17 1548-52 (2016)
PMID: 26946052

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138039 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleocapsid protein p7 Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 6.44 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
  • Canonical: P04591 (Residues: 378-432; Coverage: 11%)
Gene name: gag
Sequence domains: Zinc knuckle

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Experimental Method: X-ray solution scattering, Solution NMR
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Overview of the Nucleic-Acid Binding Properties of the HIV-1 Nucleocapsid Protein in Its Different Maturation States.
Mouhand et al. (2020)
1 more

3 mentions without citation

Review and Perspectives on the Structure-Function Relationships of the Gag Subunits of Feline Immunodeficiency Virus.
Long et al. (2021)
2 more