› 5h1j

X-ray diffraction
2Å resolution

Crystal structure of WD40 repeat domains of Gemin5

Released:
DOI: 10.2210/pdb5h1j/pdb
PDB entry 5h1j coloured by chain, front view.
PDB entry 5h1j coloured by chain, side view.
PDB entry 5h1j coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5.
Jin W, Wang Y, Liu CP, Yang N, Jin M, Cong Y, Wang M, Xu RM
Genes Dev 30 2391-2403 (2016)
PMID: 27881601

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gem-associated protein 5 Chain: A
Molecule details ›
Chain: A
Length: 734 amino acids
Theoretical weight: 81.43 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8TEQ6 (Residues: 1-726; Coverage: 48%)
Gene name: GEMIN5
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P21
Unit cell:
a: 60.258Å b: 123.592Å c: 61.732Å
α: 90° β: 119.27° γ: 90°
R-values:
R R work R free
0.159 0.156 0.199
Expression system: Spodoptera frugiperda

Quick links

Citations

6 review citations

Long Noncoding RNA in Cancer: Wiring Signaling Circuitry.
Lin et al. (2018)
5 more

3 mentions without citation

Control of the eIF4E activity: structural insights and pharmacological implications.
Romagnoli et al. (2021)
2 more