› 5gyd

X-ray diffraction
3.11Å resolution

Crystal Structure of Mdm12

Released:
DOI: 10.2210/pdb5gyd/pdb
PDB entry 5gyd coloured by chain, front view.
PDB entry 5gyd coloured by chain, side view.
PDB entry 5gyd coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex.
Jeong H, Park J, Lee C
EMBO Rep 17 1857-1871 (2016)
PMID: 27821511

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial distribution and morphology protein 12 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 272 amino acids
Theoretical weight: 30.81 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92328 (Residues: 1-271; Coverage: 100%)
Gene names: MDM12, YOL009C

Ligands and Environments

1 bound ligand:
Ligand PEE 5 x PEE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P21212
Unit cell:
a: 142.592Å b: 219.073Å c: 73.097Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.254
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Here, there, and everywhere: The importance of ER membrane contact sites.
Wu et al. (2018)
8 more

4 mentions without citation

Mechanisms of Non-Vesicular Exchange of Lipids at Membrane Contact Sites: Of Shuttles, Tunnels and, Funnels.
Egea PF. (2021)
3 more