› 5gxu

X-ray diffraction
2.3Å resolution

Cystal structure of Arabidopsis ATR2

Released:
DOI: 10.2210/pdb5gxu/pdb
PDB entry 5gxu coloured by chain, front view.
PDB entry 5gxu coloured by chain, side view.
PDB entry 5gxu coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function.
Niu G, Zhao S, Wang L, Dong W, Liu L, He Y
FEBS J 284 754-765 (2017)
PMID: 28103421

Function and Biology Details

Reaction catalysed: 
NADPH + n oxidized hemoprotein = NADP(+) + n reduced hemoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193542 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NADPH--cytochrome P450 reductase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 640 amino acids
Theoretical weight: 71.55 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9SUM3 (Residues: 73-711; Coverage: 90%)
Gene names: AR2, ATR2, At4g30210, F9N11.60
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD

Cofactor: Ligand FMN 1 x FMN
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P1
Unit cell:
a: 55.333Å b: 61.821Å c: 88.331Å
α: 97.84° β: 100.51° γ: 90.27°
R-values:
R R work R free
0.202 0.2 0.248
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Tripping the light fantastic in membrane redox biology: linking dynamic structures to function in ER electron transfer chains.
Hedison et al. (2019)
8 other articles

5 mentions without citation

Structure of the Arabidopsis thaliana NADPH-cytochrome P450 reductase 2 (ATR2) provides insight into its function.
Niu et al. (2017)
4 more