Function and Biology Details
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- ATP synthase, F0 complex, subunit C
- P-loop containing nucleoside triphosphate hydrolase
- ATP synthase, F1 complex, alpha subunit
- ATPase, OSCP/delta subunit
- ATP synthase, F0 complex, subunit C, DCCD-binding site
- V-ATPase proteolipid subunit C-like domain
- F/V-ATP synthase subunit C superfamily
- F1F0 ATP synthase subunit C superfamily
32 more domains
Structure analysis Details
Assembly composition:
hetero 22-mer (preferred)
Assembly name:
ATP Synthase (preferred)
PDBe Complex ID:
PDB-CPX-133612 (preferred)
Entry contents:
11 distinct polypeptide molecules
Macromolecules (11 distinct):
ATP synthase subunit alpha, mitochondrial
Molecule details ›
Chains: A, B, C
Length: 510 amino acids
Theoretical weight: 55.3 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 510 amino acids
Theoretical weight: 55.3 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
P19483 (Residues: 44-553; Coverage: 92%)
Sequence domains:
ATP synthase subunit beta, mitochondrial
Molecule details ›
Chains: D, E, F
Length: 482 amino acids
Theoretical weight: 51.76 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 482 amino acids
Theoretical weight: 51.76 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P00829 (Residues: 47-528; Coverage: 91%)
Sequence domains:
ATP synthase subunit gamma, mitochondrial
Molecule details ›
Chain: G
Length: 273 amino acids
Theoretical weight: 30.3 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: ATP synthase
Length: 273 amino acids
Theoretical weight: 30.3 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05631 (Residues: 26-298; Coverage: 92%)
Sequence domains: ATP synthase
ATP synthase subunit delta, mitochondrial
Molecule details ›
Chain: H
Length: 146 amino acids
Theoretical weight: 15.07 KDa
Source organism: Bos taurus
UniProt:
Sequence domains:
Length: 146 amino acids
Theoretical weight: 15.07 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05630 (Residues: 23-168; Coverage: 87%)
Sequence domains:
ATP synthase subunit epsilon, mitochondrial
Molecule details ›
Chain: I
Length: 50 amino acids
Theoretical weight: 5.66 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: Mitochondrial ATP synthase epsilon chain
Length: 50 amino acids
Theoretical weight: 5.66 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P05632 (Residues: 2-51; Coverage: 98%)
Sequence domains: Mitochondrial ATP synthase epsilon chain
ATP synthase F(0) complex subunit C1, mitochondrial
Molecule details ›
Chains: J, K, L, M, N, O, P, Q
Length: 72 amino acids
Theoretical weight: 7.29 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: ATP synthase subunit C
Length: 72 amino acids
Theoretical weight: 7.29 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P32876 (Residues: 63-134; Coverage: 53%)
Sequence domains: ATP synthase subunit C
ATP synthase subunit O, mitochondrial
Molecule details ›
Chain: S
Length: 190 amino acids
Theoretical weight: 20.99 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: ATP synthase delta (OSCP) subunit
Length: 190 amino acids
Theoretical weight: 20.99 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P13621 (Residues: 24-213; Coverage: 89%)
Sequence domains: ATP synthase delta (OSCP) subunit
ATP synthase F(0) complex subunit B1, mitochondrial
Molecule details ›
Chain: T
Length: 174 amino acids
Theoretical weight: 20.34 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
Length: 174 amino acids
Theoretical weight: 20.34 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P13619 (Residues: 76-249; Coverage: 68%)
Sequence domains: Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
ATP synthase subunit d, mitochondrial
Molecule details ›
Chain: U
Length: 124 amino acids
Theoretical weight: 14.17 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: ATP synthase D chain, mitochondrial (ATP5H)
Length: 124 amino acids
Theoretical weight: 14.17 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P13620 (Residues: 2-125; Coverage: 77%)
Sequence domains: ATP synthase D chain, mitochondrial (ATP5H)
ATP synthase-coupling factor 6, mitochondrial
Molecule details ›
Chain: V
Length: 77 amino acids
Theoretical weight: 9.12 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Mitochondrial ATP synthase coupling factor 6
Length: 77 amino acids
Theoretical weight: 9.12 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P02721 (Residues: 32-108; Coverage: 71%)
Sequence domains: Mitochondrial ATP synthase coupling factor 6
ATP synthase subunit a
Molecule details ›
Chain: W
Length: 217 amino acids
Theoretical weight: 23.72 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: ATP synthase A chain
Length: 217 amino acids
Theoretical weight: 23.72 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P00847 (Residues: 10-226; Coverage: 96%)
Sequence domains: ATP synthase A chain
