› 5f3a

X-ray diffraction
1.6Å resolution

Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14

Released:
DOI: 10.2210/pdb5f3a/pdb
PDB entry 5f3a coloured by chain, front view.
PDB entry 5f3a coloured by chain, side view.
PDB entry 5f3a coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dong J, Caflisch A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180199 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATPase family AAA domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PL18 (Residues: 981-1108; Coverage: 9%)
Gene names: ATAD2, L16, PRO2000
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand 5U9 1 x 5U9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P6522
Unit cell:
a: 79.938Å b: 79.938Å c: 137.533Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.179 0.21
Expression system: Escherichia coli

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