› 5ey3

X-ray diffraction
1.9Å resolution

X-ray structure of the thymidine phosphorylase from Salmonella typhimurium in complex with cytidine and sulphate

Released:
DOI: 10.2210/pdb5ey3/pdb
PDB entry 5ey3 coloured by chain, front view.
PDB entry 5ey3 coloured by chain, side view.
PDB entry 5ey3 coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Entry authors: Balaev VV, Lashkov AA, Gabdulkhakov AG, Betzel C, Mikhailov AM

Function and Biology Details

Reaction catalysed: 
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181394 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

4 bound ligands:
Ligand SO4 9 x SO4
Ligand GOL 2 x GOL
Ligand EDO 1 x EDO
Ligand CTN 1 x CTN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: I4
Unit cell:
a: 193.398Å b: 193.398Å c: 58.208Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.238
Expression system: Escherichia coli

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