Function and Biology Details
Reactions catalysed:
6-amino-6-deoxyfutalosine + H(2)O = dehypoxanthine futalosine + adenine
5'-deoxyadenosine + H(2)O = 5-deoxy-D-ribose + adenine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Aminodeoxyfutalosine nucleosidase (preferred)
PDBe Complex ID:
PDB-CPX-195684 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminodeoxyfutalosine nucleosidase
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 24.98 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli
UniProt:
Sequence domains: Phosphorylase superfamily
Structure domains: Nucleoside phosphorylase domain
Length: 230 amino acids
Theoretical weight: 24.98 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9ZMY2 (Residues: 2-230; Coverage: 100%)
Sequence domains: Phosphorylase superfamily
Structure domains: Nucleoside phosphorylase domain
Ligands and Environments
Experiments and Validation Details
Experimental Method:
X-ray diffraction, Neutron Diffraction
Spacegroup:
P3221
Unit cell:
a: 83.189Å
b: 83.189Å
c: 67.633Å
α: 90°
β: 90°
γ: 120°
R-values:
R
R work
R free
0.343
0.343
0.376
Expression system: Escherichia coli
