› 5bzk

X-ray diffraction
1.4Å resolution

Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule

Released:
DOI: 10.2210/pdb5bzk/pdb
PDB entry 5bzk coloured by chain, front view.
PDB entry 5bzk coloured by chain, side view.
PDB entry 5bzk coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Liu LK, Finzel BC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.86 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15379 (Residues: 21-171; Coverage: 20%)
Gene names: Cd44, Ly-24
Sequence domains: Extracellular link domain

Ligands and Environments

3 bound ligands:
Ligand DMS 1 x DMS
Ligand 4WP 1 x 4WP
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 30.804Å b: 81.745Å c: 32.279Å
α: 90° β: 118.14° γ: 90°
R-values:
R R work R free
0.188 0.188 0.209
Expression system: Escherichia coli BL21(DE3)

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