› 5bow

X-ray diffraction
1.31Å resolution

CRYSTAL STRUCTURE OF IL-38

Released:
DOI: 10.2210/pdb5bow/pdb
PDB entry 5bow coloured by chain, front view.
PDB entry 5bow coloured by chain, side view.
PDB entry 5bow coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Guenther S, Sundberg EJ

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-186763 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interleukin-1 family member 10 Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WWZ1 (Residues: 3-152; Coverage: 99%)
Gene names: FIL1T, FKSG75, IL1F10, IL1HY2, IL38, UNQ6119/PRO20041
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

1 bound ligand:
Ligand EDO 6 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Unit cell:
a: 31.264Å b: 62.514Å c: 62.55Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.139 0.138 0.16
Expression system: Escherichia coli BL21(DE3)

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