› 5a6g

Electron Microscopy
4.5Å resolution

Cryo-EM structure of the Slo2.2 Na-activated K channel

Released:
DOI: 10.2210/pdb5a6g/pdb
PDB entry 5a6g coloured by chain, front view.
PDB entry 5a6g coloured by chain, side view.
PDB entry 5a6g coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.
Hite RK, Yuan P, Li Z, Hsuing Y, Walz T, MacKinnon R
Nature 527 198-203 (2015)
PMID: 26436452
Related structures: EMD-3064

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165427 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 11.85 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
Potassium channel subfamily T member 1 Chain: B
Molecule details ›
Chain: B
Length: 94 amino acids
Theoretical weight: 10.72 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8QFV0 (Residues: 244-337; Coverage: 8%)
Gene names: KCNT1, SLACK
Sequence domains: Ion channel

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-3064
Expression system: Spodoptera frugiperda

Quick links

Citations

28 review citations

Unravelling biological macromolecules with cryo-electron microscopy.
Fernandez-Leiro et al. (2016)
27 more

2 mentions without citation

Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.
Hite et al. (2015)
1 more