› 5a1k

X-ray diffraction
2.9Å resolution

Crystal structure of calcium-free human adseverin domains A1-A3

Released:
DOI: 10.2210/pdb5a1k/pdb
PDB entry 5a1k coloured by chain, front view.
PDB entry 5a1k coloured by chain, side view.
PDB entry 5a1k coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Calcium-controlled conformational choreography in the N-terminal half of adseverin.
Chumnarnsilpa S, Robinson RC, Grimes JM, Leyrat C
Nat Commun 6 8254 (2015)
PMID: 26365202

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195387 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Scinderin Chains: A, B
Molecule details ›
Chains: A, B
Length: 344 amino acids
Theoretical weight: 38.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6U3 (Residues: 6-349; Coverage: 48%)
Gene names: KIAA1905, SCIN
Sequence domains: Gelsolin repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 135.41Å b: 65.25Å c: 105.19Å
α: 90° β: 118.27° γ: 90°
R-values:
R R work R free
0.24 0.24 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology.
Brosey et al. (2019)
3 more

1 mention without citation

Calcium-controlled conformational choreography in the N-terminal half of adseverin.
Chumnarnsilpa et al. (2015)