› 4mb6

X-ray diffraction
1.81Å resolution

Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis.

Released:
DOI: 10.2210/pdb4mb6/pdb
PDB entry 4mb6 coloured by chain, front view.
PDB entry 4mb6 coloured by chain, side view.
PDB entry 4mb6 coloured by chain, top view.
Source organism: Yersinia pseudotuberculosis IP 32953
Entry authors: Pavithra GC, Kim J, Hegde RP, Almo SC, Ramagopal UA, New York Structural Genomics Research Consortium (NYSGRC)

Function and Biology Details

Reaction catalysed: 
AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179272 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenine phosphoribosyltransferase Chain: A
Molecule details ›
Chain: A
Length: 187 amino acids
Theoretical weight: 20.17 KDa
Source organism: Yersinia pseudotuberculosis IP 32953
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q66DQ2 (Residues: 1-187; Coverage: 100%)
Gene names: YPTB0991, apt
Sequence domains: Phosphoribosyl transferase domain
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2
Unit cell:
a: 58.56Å b: 78.38Å c: 54.01Å
α: 90° β: 112.98° γ: 90°
R-values:
R R work R free
0.187 0.184 0.238
Expression system: Escherichia coli BL21(DE3)

Quick links