› 4z63

X-ray diffraction
2.51Å resolution

The plant peptide hormone receptor in arabidopsis

Released:
DOI: 10.2210/pdb4z63/pdb
PDB entry 4z63 coloured by chain, front view.
PDB entry 4z63 coloured by chain, side view.
PDB entry 4z63 coloured by chain, top view.
Source organisms:
Primary publication:
Allosteric receptor activation by the plant peptide hormone phytosulfokine.
Wang J, Li H, Han Z, Zhang H, Wang T, Lin G, Chang J, Yang W, Chai J
Nature 525 265-8 (2015)
PMID: 26308901

Function and Biology Details

Reactions catalysed: 
ATP + a protein = ADP + a phosphoprotein
GTP = 3',5'-cyclic GMP + diphosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165393 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phytosulfokine receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 631 amino acids
Theoretical weight: 69.88 KDa
Source organism: Arabidopsis thaliana
Expression system: Insect cell expression vector pTIE1
UniProt:
  • Canonical: Q9ZVR7 (Residues: 24-648; Coverage: 63%)
Gene names: At2g02220, F5O4.1, PSKR, PSKR1
Sequence domains:
Phytosulfokine Chain: P
Molecule details ›
Chain: P
Length: 5 amino acids
Theoretical weight: 847 Da
Source organism: Arabidopsis
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NAG 9 x NAG
1 modified residue:
Ligand TYS 2 x TYS

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P4322
Unit cell:
a: 92.892Å b: 92.892Å c: 242.492Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.229 0.276
Expression systems:
  • Insect cell expression vector pTIE1
  • Not provided

Quick links

Citations

37 review citations

Regulation of pattern recognition receptor signalling in plants.
Couto et al. (2016)
36 more

6 mentions without citation

Plant Leucine-Rich Repeat Receptor Kinase (LRR-RK): Structure, Ligand Perception, and Activation Mechanism.
Chakraborty et al. (2019)
5 more