› 4xia

X-ray diffraction
2.3Å resolution

STRUCTURES OF D-XYLOSE ISOMERASE FROM ARTHROBACTER STRAIN B3728 CONTAINING THE INHIBITORS XYLITOL AND D-SORBITOL AT 2.5 ANGSTROMS AND 2.3 ANGSTROMS RESOLUTION, RESPECTIVELY

Released:
DOI: 10.2210/pdb4xia/pdb
PDB entry 4xia coloured by chain, front view.
PDB entry 4xia coloured by chain, side view.
PDB entry 4xia coloured by chain, top view.
Source organism: Arthrobacter sp. NRRL B3728
Primary publication:
Structures of D-xylose isomerase from Arthrobacter strain B3728 containing the inhibitors xylitol and D-sorbitol at 2.5 A and 2.3 A resolution, respectively.
Henrick K, Collyer CA, Blow DM
J Mol Biol 208 129-57 (1989)
PMID: 2769749

Function and Biology Details

Reaction catalysed: 
Alpha-D-xylopyranose = alpha-D-xylufuranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146092 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xylose isomerase Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 42.95 KDa
Source organism: Arthrobacter sp. NRRL B3728
Expression system: Not provided
UniProt:
  • Canonical: P12070 (Residues: 3-395; Coverage: 100%)
Gene name: xylA
Sequence domains: Xylose isomerase-like TIM barrel
Structure domains: Divalent-metal-dependent TIM barrel enzymes

Ligands and Environments

2 bound ligands:
Ligand SOR 2 x SOR
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3121
Unit cell:
a: 105.8Å b: 105.8Å c: 153.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.147 not available not available
Expression system: Not provided

Quick links

Citations

2 review citations

Molecular and industrial aspects of glucose isomerase.
Bhosale et al. (1996)
1 more

3 mentions without citation

LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation.
Huang et al. (2006)
2 more