Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Influenza RNA-dependent RNA polymerase subunit PB1
- PB2, C-terminal
- Influenza RNA-dependent RNA polymerase subunit PB2
- RNA-directed RNA polymerase, negative-strand RNA virus
- Influenza RNA-dependent RNA polymerase subunit PA
- Polymerase acidic protein
- Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-178406 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (5 distinct):
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-1
Spacegroup:
P6322
Expression systems:
- Trichoplusia ni
- Not provided