› 4u6o

X-ray diffraction
1.3Å resolution

STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2

Released:
DOI: 10.2210/pdb4u6o/pdb
PDB entry 4u6o coloured by chain, front view.
PDB entry 4u6o coloured by chain, side view.
PDB entry 4u6o coloured by chain, top view.
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Entry authors: Fukushima K, Takimoto-Kamimura M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137008 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polymerase basic protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 18.89 KDa
Source organism: Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: P03428 (Residues: 318-483; Coverage: 22%)
Gene name: PB2
Sequence domains: Influenza RNA polymerase PB2 CAP binding domain

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21
Unit cell:
a: 38.218Å b: 64.377Å c: 64.765Å
α: 90° β: 91.04° γ: 90°
R-values:
R R work R free
0.21 0.209 0.227
Expression system: Escherichia coli

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