› 4u4h

X-ray diffraction
2.05Å resolution

Crystal Structure of HSV-1 UL21 N-terminal Domain

Released:
DOI: 10.2210/pdb4u4h/pdb
PDB entry 4u4h coloured by chain, front view.
PDB entry 4u4h coloured by chain, side view.
PDB entry 4u4h coloured by chain, top view.
Source organism: Human alphaherpesvirus 1 strain 17
Primary publication:
The unusual fold of herpes simplex virus 1 UL21, a multifunctional tegument protein.
Metrick CM, Chadha P, Heldwein EE
J Virol 89 2979-84 (2015)
PMID: 25540382

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-145202 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tegument protein UL21 Chain: A
Molecule details ›
Chain: A
Length: 209 amino acids
Theoretical weight: 23.18 KDa
Source organism: Human alphaherpesvirus 1 strain 17
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10205 (Residues: 1-198; Coverage: 37%)
Gene name: UL21
Sequence domains: Herpesvirus UL21

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P6322
Unit cell:
a: 108.346Å b: 108.346Å c: 65.236Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.166 0.221
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Alphaherpesvirus glycoprotein E: A review of its interactions with other proteins of the virus and its application in vaccinology.
Ning et al. (2022)
9 other articles

3 mentions without citation

The unusual fold of herpes simplex virus 1 UL21, a multifunctional tegument protein.
Metrick et al. (2015)
2 more