› 4tsc

X-ray diffraction
1.92Å resolution

Structure of a lysozyme antibody complex

Released:
DOI: 10.2210/pdb4tsc/pdb
PDB entry 4tsc coloured by chain, front view.
PDB entry 4tsc coloured by chain, side view.
PDB entry 4tsc coloured by chain, top view.
Source organisms:
Entry author: Wensley B

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208277 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme
FAb Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.48 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
FAb Light Chain Chain: L
Molecule details ›
Chain: L
Length: 217 amino acids
Theoretical weight: 22.79 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21212
Unit cell:
a: 78.629Å b: 129.734Å c: 59.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.209 0.232
Expression system: Homo sapiens

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