PDB 4qfr structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reactions catalysed:

ATP + a protein = ADP + a phosphoprotein

ATP + [tau protein] = ADP + [tau protein] phosphate

ATP + [hydroxymethylglutaryl-CoA reductase (NADPH)] = ADP + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate

Biochemical function:

protein-containing complex binding

Biological process:

cellular response to nutrient levels

Cellular component:

protein-containing complex

Sequence domains:

7 more domains

Structure analysis Details

Assemblies composition:

hetero trimer (preferred)
hetero hexamer

Assembly name:

5'-AMP-activated protein kinase (preferred)

PDBe Complex ID:

PDB-CPX-157065 (preferred)

Entry contents:

3 distinct polypeptide molecules

Macromolecules (3 distinct):

5'-AMP-activated protein kinase catalytic subunit alpha-1 Chain: A

Molecule details ›

Chain: A
Length: 503 amino acids
Theoretical weight: 57.78 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:

Canonical: P54645 (Residues: 11-559; Coverage: 90%)

Gene names: Ampk1, Prkaa1
Sequence domains:

5'-AMP-activated protein kinase subunit beta-1 Chain: B

Molecule details ›

Chain: B
Length: 204 amino acids
Theoretical weight: 23.05 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:

Canonical: P80386 (Residues: 68-270; Coverage: 75%)

Gene name: Prkab1
Sequence domains:

Structure domains: Double Stranded RNA Binding Domain

5'-AMP-activated protein kinase subunit gamma-1 Chain: C

Molecule details ›

Chain: C
Length: 330 amino acids
Theoretical weight: 37.43 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt: