› 4oek

X-ray diffraction
2.47Å resolution

Crystal Structure of the Complex of goat Lactoperoxidase with Phenylethylamine at 2.47 A Resolution

Released:
DOI: 10.2210/pdb4oek/pdb
PDB entry 4oek coloured by chain, front view.
PDB entry 4oek coloured by chain, side view.
PDB entry 4oek coloured by chain, top view.
Source organism: Capra hircus
Entry authors: Kumar M, Singh RP, Sinha M, Bhushan A, Kaur P, Sharma S, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-105074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lactoperoxidase Chain: A
Molecule details ›
Chain: A
Length: 595 amino acids
Theoretical weight: 67.61 KDa
Source organism: Capra hircus
UniProt:
  • Canonical: A0A452E9Y6 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase
Structure domains: Haem peroxidase domain superfamily, animal type

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
6 bound ligands:
Ligand NAG 3 x NAG
Ligand CA 1 x CA
Ligand IOD 13 x IOD
Ligand SCN 1 x SCN
Ligand EDO 5 x EDO
Ligand PEA 1 x PEA
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 53.166Å b: 79.891Å c: 75.284Å
α: 90° β: 101.8° γ: 90°
R-values:
R R work R free
0.208 0.204 0.281

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