› 4mm1

X-ray diffraction
2.8Å resolution

Function and Biology Details

Reaction catalysed: 
Geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo hexamer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127844 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Geranylgeranylglyceryl phosphate synthase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 250 amino acids
Theoretical weight: 26.79 KDa
Source organism: Methanothermobacter thermautotrophicus str. Delta H
Expression system: Escherichia coli
UniProt:
  • Canonical: O26652 (Residues: 1-245; Coverage: 100%)
Gene name: MTH_552
Sequence domains: PcrB family
Structure domains: FMN-linked oxidoreductases

Ligands and Environments

2 bound ligands:
Ligand 1GP 6 x 1GP
Ligand PGE 6 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: C2
Unit cell:
a: 143.675Å b: 148.756Å c: 91.503Å
α: 90° β: 109.5° γ: 90°
R-values:
R R work R free
0.204 0.2 0.271
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST): A web tool for generating protein sequence similarity networks.
Gerlt et al. (2015)
1 more

5 mentions without citation

Biosynthesis of archaeal membrane ether lipids.
Jain et al. (2014)
4 more