› 4kdd

X-ray diffraction
1.9Å resolution

Structure of Mycobacterium tuberculosis ribosome recycling factor in presence of detergent

Released:
DOI: 10.2210/pdb4kdd/pdb
PDB entry 4kdd coloured by chain, front view.
PDB entry 4kdd coloured by chain, side view.
PDB entry 4kdd coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Molecular flexibility of Mycobacterium tuberculosis ribosome recycling factor and its functional consequences: an exploration involving mutants.
Selvaraj M, Govindan A, Seshadri A, Dubey B, Varshney U, Vijayan M
J Biosci 38 845-55 (2013)
PMID: 24296887

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161527 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome-recycling factor Chain: A
Molecule details ›
Chain: A
Length: 185 amino acids
Theoretical weight: 20.86 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WGY1 (Residues: 1-185; Coverage: 100%)
Gene names: MTCY274.13c, Rv2882c, frr
Sequence domains: Ribosome recycling factor
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CD 2 x CD
Ligand DMU 1 x DMU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 56.37Å b: 33.72Å c: 61.51Å
α: 90° β: 112.84° γ: 90°
R-values:
R R work R free
0.251 0.249 0.27
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Comparative secretomics reveals novel virulence-associated factors of Vibrio parahaemolyticus.
He et al. (2015)

1 mention without citation

A Structural View at Vaccine Development against M. tuberculosis.
Romano et al. (2023)