› 4jvu

X-ray diffraction
1.3Å resolution

IgM C2-domain from mouse

Released:
DOI: 10.2210/pdb4jvu/pdb
PDB entry 4jvu coloured by chain, front view.
PDB entry 4jvu coloured by chain, side view.
PDB entry 4jvu coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Müller R, Gräwert MA, Kern T, Madl T, Peschek J, Sattler M, Groll M, Buchner J
Proc Natl Acad Sci U S A 110 10183-8 (2013)
PMID: 23733956

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134960 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mu' chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 12.77 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P01872 (Residues: 103-217; Coverage: 25%)
Gene names: Igh-6, Ighm
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 92.44Å b: 44.78Å c: 54.57Å
α: 90° β: 118.1° γ: 90°
R-values:
R R work R free
0.141 0.138 0.168
Expression system: Escherichia coli BL21

Quick links

Citations

10 review citations

Human IgG4: a structural perspective.
Davies et al. (2015)
9 more

12 mentions without citation

High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.
Müller et al. (2013)
11 more