› 4jiz

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164626 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MOB kinase activator 1A Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 20.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H8S9 (Residues: 40-211; Coverage: 80%)
Gene names: C2orf6, MOB1A, MOB4B, MOBK1B, MOBKL1B
Sequence domains: Mob1/phocein family
Structure domains: MOB kinase activator
phosphopeptide Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 1.08 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P21
Unit cell:
a: 34.49Å b: 59.6Å c: 53.42Å
α: 90° β: 104.65° γ: 90°
R-values:
R R work R free
0.231 0.178 0.226
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

12 review citations

Centrosomes as signalling centres.
Arquint et al. (2014)
11 more

3 mentions without citation

Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways.
Duhart et al. (2020)
2 more