› 4jbz

X-ray diffraction
2.4Å resolution

Structure of Mcm10 coiled-coil region

Released:
DOI: 10.2210/pdb4jbz/pdb
PDB entry 4jbz coloured by chain, front view.
PDB entry 4jbz coloured by chain, side view.
PDB entry 4jbz coloured by chain, top view.
Source organisms:
Primary publication:
Mcm10 self-association is mediated by an N-terminal coiled-coil domain.
Du W, Josephrajan A, Adhikary S, Bowles T, Bielinsky AK, Eichman BF
PLoS One 8 e70518 (2013)
PMID: 23894664

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142574 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; Protein MCM10 homolog Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 403 amino acids
Theoretical weight: 44.13 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • Canonical: Q5EAW4 (Residues: 95-124; Coverage: 4%)
Gene names: JW3994, b4034, malE, mcm10
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: C2
Unit cell:
a: 187.377Å b: 116.618Å c: 73.395Å
α: 90° β: 103.48° γ: 90°
R-values:
R R work R free
0.166 0.164 0.205
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Eukaryotic DNA replication: Orchestrated action of multi-subunit protein complexes.
Kang et al. (2018)
1 more

4 mentions without citation

Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks.
Baxley et al. (2017)
3 more