› 4j4e

X-ray diffraction
2.4Å resolution

Structure of P51G Cyanovirin-N swapped trimer in the P212121 space group

Released:
DOI: 10.2210/pdb4j4e/pdb
PDB entry 4j4e coloured by chain, front view.
PDB entry 4j4e coloured by chain, side view.
PDB entry 4j4e coloured by chain, top view.
Source organism: Nostoc ellipsosporum
Primary publication:
Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Koharudin LM, Liu L, Gronenborn AM
Proc Natl Acad Sci U S A 110 7702-7 (2013)
PMID: 23610431

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyanovirin-N Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 101 amino acids
Theoretical weight: 10.98 KDa
Source organism: Nostoc ellipsosporum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P81180 (Residues: 1-101; Coverage: 100%)
Sequence domains: CVNH domain
Structure domains: Cyanovirin-N

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 61.694Å b: 81.006Å c: 137.546Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.237 0.281
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Cyanobacterial lectins characteristics and their role as antiviral agents.
Singh et al. (2017)
3 more

1 mention without citation

Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates.
Koharudin et al. (2013)