› 4it9

X-ray diffraction
1.7Å resolution

Structure of Bacterial Enzyme

Released:
DOI: 10.2210/pdb4it9/pdb
PDB entry 4it9 coloured by chain, front view.
PDB entry 4it9 coloured by chain, side view.
PDB entry 4it9 coloured by chain, top view.
Source organism: Synechococcus sp. PCC 7002
Primary publication:
Structural basis for a cofactor-dependent oxidation protection and catalysis of cyanobacterial succinic semialdehyde dehydrogenase.
Park J, Rhee S
J Biol Chem 288 15760-70 (2013)
PMID: 23589281

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109429 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldehyde dehydrogenase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 456 amino acids
Theoretical weight: 49.26 KDa
Source organism: Synechococcus sp. PCC 7002
Expression system: Escherichia coli
UniProt:
  • Canonical: B1XMM6 (Residues: 1-454; Coverage: 100%)
Gene name: SYNPCC7002_A2771
Sequence domains: Aldehyde dehydrogenase family
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand EDO 31 x EDO
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P212121
Unit cell:
a: 42.779Å b: 115.34Å c: 179.267Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.183 0.206
Expression system: Escherichia coli

Quick links

Citations

10 citation in other articles

Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action.
Huo et al. (2015)
9 more

1 mention without citation

Structural basis for a cofactor-dependent oxidation protection and catalysis of cyanobacterial succinic semialdehyde dehydrogenase.
Park et al. (2013)