› 4i92

X-ray diffraction
1.6Å resolution

Structure of the BSK8 kinase domain

Released:
DOI: 10.2210/pdb4i92/pdb
PDB entry 4i92 coloured by chain, front view.
PDB entry 4i92 coloured by chain, side view.
PDB entry 4i92 coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Structural characterization of the RLCK family member BSK8: a pseudokinase with an unprecedented architecture.
Grütter C, Sreeramulu S, Sessa G, Rauh D
J Mol Biol 425 4455-67 (2013)
PMID: 23911552

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190317 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase BSK8 Chain: A
Molecule details ›
Chain: A
Length: 300 amino acids
Theoretical weight: 34.39 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9FHD7 (Residues: 40-328; Coverage: 59%)
Gene names: At5g41260, BSK8, K1O13.5
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P21
Unit cell:
a: 35.09Å b: 76.99Å c: 50.57Å
α: 90° β: 104.86° γ: 90°
R-values:
R R work R free
0.161 0.16 0.184
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Receptor-Like Cytoplasmic Kinases: Central Players in Plant Receptor Kinase-Mediated Signaling.
Liang et al. (2018)
3 more

3 mentions without citation

Prospects for pharmacological targeting of pseudokinases.
Kung et al. (2019)
2 more