› 4hbg

X-ray diffraction
2.27Å resolution

Crystal structure of Saccharomyces cerevisiae 3 oxoacyl-[acyl carrier protein]-reductase complexed with NADPH (form2)

Released:
DOI: 10.2210/pdb4hbg/pdb
PDB entry 4hbg coloured by chain, front view.
PDB entry 4hbg coloured by chain, side view.
PDB entry 4hbg coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Entry authors: Zhang YJ, Gao YX, Teng MK

Function and Biology Details

Reaction catalysed: 
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl-carrier-protein] + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153011 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] reductase Chain: A
Molecule details ›
Chain: A
Length: 286 amino acids
Theoretical weight: 32.29 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: P35731 (Residues: 1-278; Coverage: 100%)
Gene names: OAR1, YKL055C
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments


Cofactor: Ligand NDP 1 x NDP
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P6122
Unit cell:
a: 50.8Å b: 50.8Å c: 415.041Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.247 0.245 0.285
Expression system: Escherichia coli

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