4gxl

X-ray diffraction
2.02Å resolution

The crystal structure of Galectin-8 C-CRD in complex with NDP52

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-126161 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Galectin-8 Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 17.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00214 (Residues: 186-317; Coverage: 42%)
Gene name: LGALS8
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls
Calcium-binding and coiled-coil domain-containing protein 2 Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.51 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13137 (Residues: 368-381; Coverage: 3%)
Gene names: CALCOCO2, NDP52

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C222
Unit cell:
a: 76.087Å b: 124.826Å c: 43.737Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.177 0.216
Expression systems:
  • Escherichia coli
  • Not provided