› 4gx6

X-ray diffraction
2.5Å resolution

AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Mutation E192Q

Released:
DOI: 10.2210/pdb4gx6/pdb
PDB entry 4gx6 coloured by chain, front view.
PDB entry 4gx6 coloured by chain, side view.
PDB entry 4gx6 coloured by chain, top view.
Source organism: Sus scrofa
Entry authors: Gao Y, Honzatko RB

Function and Biology Details

Reaction catalysed: 
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132778 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fructose-1,6-bisphosphatase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 337 amino acids
Theoretical weight: 36.69 KDa
Source organism: Sus scrofa
Expression system: Escherichia coli
UniProt:
  • Canonical: P00636 (Residues: 2-338; Coverage: 100%)
Gene names: FBP, FBP1
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand F6P 2 x F6P
Ligand MG 4 x MG
Ligand AMP 2 x AMP
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21212
Unit cell:
a: 59.923Å b: 165.341Å c: 79.112Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.211 0.273
Expression system: Escherichia coli

Quick links