› 4ga9

X-ray diffraction
1.88Å resolution

Crystal Structure of Rat Galectin-1 in Complex with Lactose

Released:
DOI: 10.2210/pdb4ga9/pdb
PDB entry 4ga9 coloured by chain, front view.
PDB entry 4ga9 coloured by chain, side view.
PDB entry 4ga9 coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Segev O, Hirsch JA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145917 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 134 amino acids
Theoretical weight: 14.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P11762 (Residues: 2-135; Coverage: 99%)
Gene name: Lgals1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: F222
Unit cell:
a: 106.388Å b: 106.44Å c: 107.978Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.27
Expression system: Escherichia coli BL21(DE3)

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