4fi9

X-ray diffraction
3.05Å resolution

Structure of human SUN-KASH complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-186782 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SUN domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 21.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UH99 (Residues: 523-717; Coverage: 27%)
Gene names: FRIGG, KIAA0668, RAB5IP, SUN2, UNC84B
Sequence domains: Sad1 / UNC-like C-terminal
Structure domains: Galactose-binding domain-like
Nesprin-2 Chain: B
Molecule details ›
Chain: B
Length: 14 amino acids
Theoretical weight: 1.65 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8WXH0 (Residues: 6872-6885; Coverage: 0%)
Gene names: KIAA1011, NUA, SYNE2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: R32
Unit cell:
a: 79.835Å b: 79.835Å c: 280.221Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.241 0.31
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided