› 4ev2

X-ray diffraction
2.18Å resolution

Crystal structure of copper amine oxidase-1 from Hansenula polymorpha in complex with ethylamine

Released:
DOI: 10.2210/pdb4ev2/pdb
PDB entry 4ev2 coloured by chain, front view.
PDB entry 4ev2 coloured by chain, side view.
PDB entry 4ev2 coloured by chain, top view.
Source organism: Ogataea angusta
Entry authors: Klema VJ, Solheid CJ, Wilmot CM

Function and Biology Details

Reaction catalysed: 
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146322 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisomal primary amine oxidase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 692 amino acids
Theoretical weight: 77.66 KDa
Source organism: Ogataea angusta
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P12807 (Residues: 1-692; Coverage: 100%)
Gene name: AMO
Sequence domains:
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand GOL 31 x GOL
Ligand CU 6 x CU
Ligand PEO 4 x PEO
Ligand NEH 6 x NEH
Ligand PO4 1 x PO4
1 modified residue:
Ligand TYQ 6 x TYQ

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 104.408Å b: 232.834Å c: 105.119Å
α: 90° β: 96.66° γ: 90°
R-values:
R R work R free
0.153 0.15 0.201
Expression system: Saccharomyces cerevisiae

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