› 4efv

X-ray diffraction
2.32Å resolution

Crystal structure of OIF from Llama seminal plasma

Released:
DOI: 10.2210/pdb4efv/pdb
PDB entry 4efv coloured by chain, front view.
PDB entry 4efv coloured by chain, side view.
PDB entry 4efv coloured by chain, top view.
Source organism: Lama glama
Primary publication:
The nerve of ovulation-inducing factor in semen.
Ratto MH, Leduc YA, Valderrama XP, van Straaten KE, Delbaere LT, Pierson RA, Adams GP
Proc Natl Acad Sci U S A 109 15042-7 (2012)
PMID: 22908303

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125400 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nerve growth factor-related domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 13.05 KDa
Source organism: Lama glama
UniProt:
  • Canonical: J9PBR9 (Residues: 1-117; Coverage: 100%)
Sequence domains: Nerve growth factor family
Structure domains: Cystine-knot cytokines

Ligands and Environments

2 bound ligands:
Ligand PO4 2 x PO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: I41
Unit cell:
a: 108.93Å b: 108.93Å c: 49.83Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.247

Quick links

Citations

13 review citations

Sexual conflict and seminal fluid proteins: a dynamic landscape of sexual interactions.
Sirot et al. (2014)
12 more

4 mentions without citation

Small Endogenous Ligands Modulation of Nerve Growth Factor Bioactivity: A Structural Biology Overview.
Paoletti et al. (2021)
3 more