› 4d69

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138338 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Lectin Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 253 amino acids
Theoretical weight: 27.6 KDa
Source organism: Glycine max
UniProt:
  • Canonical: P05046 (Residues: 33-285; Coverage: 100%)
Gene name: LE1
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls
SHORT ANTIGEN PEPTIDE Chains: O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 5 amino acids
Theoretical weight: 560 Da
Source organism: synthetic construct

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand A2G 12 x A2G
Ligand MN 24 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P32
Unit cell:
a: 114.232Å b: 114.232Å c: 202.893Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.23 0.274

Quick links

Citations

2 review citations

Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides.
Martínez-Sáez et al. (2017)
1 more

3 mentions without citation

Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy.
Poiroux et al. (2017)
2 more