› 4d3y

X-ray diffraction
2.4Å resolution

The structure of inactive prolegumain from chinese hamster.

Released:
DOI: 10.2210/pdb4d3y/pdb
PDB entry 4d3y coloured by chain, front view.
PDB entry 4d3y coloured by chain, side view.
PDB entry 4d3y coloured by chain, top view.
Source organism: Cricetulus griseus
Entry authors: Li W, Heinz DW, Krausze J

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins and small molecule substrates at -Asn-|-Xaa- bonds.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124344 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Legumain Chain: A
Molecule details ›
Chain: A
Length: 408 amino acids
Theoretical weight: 46.63 KDa
Source organism: Cricetulus griseus
UniProt:
  • Canonical: G3I1H5 (Residues: 31-438; Coverage: 98%)
Gene names: I79_017232, Lgmn
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NAG 3 x NAG
Ligand GOL 1 x GOL
2 modified residues:
Ligand SNN 1 x SNN
Ligand CSX 1 x CSX

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, DESY BEAMLINE P11
Spacegroup: P212121
Unit cell:
a: 38.27Å b: 60.33Å c: 153.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.168 0.241

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