› 4a4p

X-ray diffraction
2Å resolution

crystal structure of the Sec7 domain from human cytohesin1

Released:
DOI: 10.2210/pdb4a4p/pdb
PDB entry 4a4p coloured by chain, front view.
PDB entry 4a4p coloured by chain, side view.
PDB entry 4a4p coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zeeh JC, Thompson AW, Cherfils J, Biou V

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytohesin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 192 amino acids
Theoretical weight: 22.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q15438 (Residues: 63-248; Coverage: 47%)
Gene names: CYTH1, D17S811E, PSCD1
Sequence domains: Sec7 domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P21
Unit cell:
a: 47.09Å b: 80.28Å c: 51.9Å
α: 90° β: 90.17° γ: 90°
R-values:
R R work R free
0.176 0.174 0.222
Expression system: Escherichia coli BL21

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