› 4a2g

X-ray diffraction
1.8Å resolution

Coriolopsis gallica laccase collected at 8.98 keV

Released:
DOI: 10.2210/pdb4a2g/pdb
PDB entry 4a2g coloured by chain, front view.
PDB entry 4a2g coloured by chain, side view.
PDB entry 4a2g coloured by chain, top view.
Source organism: Coriolopsis gallica
Primary publication:
Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase.
De la Mora E, Lovett JE, Blanford CF, Garman EF, Valderrama B, Rudino-Pinera E
Acta Crystallogr D Biol Crystallogr 68 564-77 (2012)
PMID: 22525754

Function and Biology Details

Reaction catalysed: 
4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173070 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Laccase Chain: A
Molecule details ›
Chain: A
Length: 496 amino acids
Theoretical weight: 52.8 KDa
Source organism: Coriolopsis gallica
UniProt:
  • Canonical: Q1W6B1 (Residues: 22-517; Coverage: 100%)
Gene name: lac1
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand CU 2 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 56.011Å b: 85.23Å c: 151.514Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.157 0.188

Quick links

Citations

4 review citations

Three-dimensional structures of laccases.
Hakulinen et al. (2015)
3 more

1 mention without citation

Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase.
De la Mora et al. (2012)