Function and Biology Details
Reactions catalysed:
Glycolate + NADP(+) = glyoxylate + NADPH
4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- 3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain
- 6-phosphogluconate dehydrogenase, domain 2
- 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
- 3-hydroxyisobutyrate dehydrogenase-related, conserved site
- 6-phosphogluconate dehydrogenase, NADP-binding
- NAD(P)-binding domain superfamily
- 3-hydroxyisobutyrate dehydrogenase-related
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
Glyoxylate/succinic semialdehyde reductase 1 (preferred)
PDBe Complex ID:
PDB-CPX-192310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glyoxylate/succinic semialdehyde reductase 1
Molecule details ›
Chain: A
Length: 310 amino acids
Theoretical weight: 33.03 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 310 amino acids
Theoretical weight: 33.03 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9LSV0 (Residues: 1-289; Coverage: 100%)
Sequence domains:
- NAD binding domain of 6-phosphogluconate dehydrogenase
- NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
