3bp5

X-ray diffraction
1.8Å resolution

Crystal structure of the mouse PD-1 and PD-L2 complex

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Programmed cell death protein 1 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.18 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02242 (Residues: 34-150; Coverage: 44%)
Gene names: Pd1, Pdcd1
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Programmed cell death 1 ligand 2 Chain: B
Molecule details ›
Chain: B
Length: 202 amino acids
Theoretical weight: 22.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WUL5 (Residues: 20-220; Coverage: 88%)
Gene names: B7dc, Btdc, Cd273, Pdcd1lg2, Pdl2
Sequence domains: CD80-like C2-set immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21
Unit cell:
a: 43.933Å b: 84.056Å c: 52.108Å
α: 90° β: 107.88° γ: 90°
R-values:
R R work R free
0.192 0.19 0.228
Expression system: Escherichia coli